L-Selectin/CD62L Antibody (OX-85) [FITC] Summary
Made to Rat CD62L
Membrane; single pass type I membrane protein.
NB100-63968 recognizes rat L-selectin (CD62L). In rats CD62L is expressed by a subset of thymocytes, predominantly single positive CD4 or CD8 cells. Expression of rat CD62L is weak, and sensitive detection systems (e.g.. 3 layer biotin - streptavidin techniques) are recommended on some tissues.
Protein G purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
FITC (A=495, E=519)
PBS (pH 7.4)
0.09% Sodium Azide
Protein G purified
Alternate Names for L-Selectin/CD62L Antibody (OX-85) [FITC]
- CD62L antigen
- Leukocyte adhesion molecule 1
- Leukocyte surface antigen Leu-8
- Leukocyte-endothelial cell adhesion molecule 1
- LYAM1CD62 antigen-like family member L
- Lymph node homing receptor
- lymphocyte adhesion molecule 1
- pln homing receptor
- selectin L
The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. Human CD62L (L Selectin) is comprised of an aminoterminal C type lectin binding domain, an epidermal growth factor like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells. It is expressed on bone marrow myeloid progenitor cells, erythroid precursor cells and some thymocytes. It is preferentially localized to the tips of lymphocytes and polymorphonuclear cells microvilli. Bioactive soluble L Selectin derived from lymphocytes and neutrophils is present in normal and pathological biological fluids.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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