Kv4.2 Antibody (S57-1)

Images

 
Western Blot: Kv4.2 Antibody (S57-1) [NBP1-47649] - Analysis on rat brain membrane tissues using a 1:1000 dilution.
Immunohistochemistry-Paraffin: Kv4.2 Antibody (S57-1) [NBP1-47649] - Mouse cerebellum. Strong membrane positivity of neurons and fibers of cerebellum. White matter clearly negative.

Product Details

Summary
Product Discontinued
View other related Kv4.2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-47649
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Kv4.2 Antibody (S57-1) Summary

Immunogen
Synthetic peptide amino acids 209-225 (extracellular S1-S2 loop) of rat Kv4.2 (CGSSPGHIKELPSGERY) (NP_113918.2).
Specificity
The product is specific for Kv4.2. There is no cross-reactivity against Kv4.3.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KCND2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 0.1-1.0 ug/ml
  • Immunoprecipitation 1:10-1:500
Theoretical MW
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-47649 in the following applications:

  • IP
    1 publication

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 50% Glycerol
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for Kv4.2 Antibody (S57-1)

  • potassium voltage-gated channel, Shal-related subfamily, member 2
  • RK5
  • voltage-gated potassium channel Kv4.2
  • voltage-sensitive potassium channel

Background

Kv4.2, a voltage-gated K+ (Kv) channel subunit, has been suggested to be the key component of the subthreshold A-type K+ currents (I(SA)s) recorded from the specific subcellular compartments of certain CNS neurons (1). A-type channels, encoded by the pore-forming alpha-subunits of the Kv4.x family, are particularly important in regulating membrane excitability in the CNS and the heart. Kv4.2 is a Shal-type potassium channel that passes an A-type current and is localized to dendrites and cell bodies in the hippocampus (2). Deletion of the Kv4.2 gene and a loss of Kv4.2 protein resulted in a specific and near-complete elimination of A-type K+ currents from the apical dendrites of CA1 pyramidal neurons. The absence of dendritic Kv4.2-encoded A-type K+ currents led to an increase of bAP amplitude and an increase of concurrent Ca2+ influx (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-19315
Species: Hu
Applications: WB
NBP1-89691
Species: Hu
Applications: IHC, IHC-P
H00030819-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, RNAi
NBP2-38498
Species: Hu
Applications: IHC, IHC-P
NBP2-33891
Species: Hu
Applications: IHC, IHC-P
NBP1-81336
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-42802
Species: Hu, Mu, Rt, Po, Bv, Ca, Xp, Ze
Applications: WB, ICC/IF, IP
NBP2-19020
Species: Hu, Mu, Rt, Po, Bv
Applications: WB
NBP2-30049
Species: Hu, Mu
Applications: WB, ICC/IF, IHC-P
H00003736-B01P
Species: Hu
Applications: WB
AF2180
Species: Hu
Applications: WB, Simple Western, IP
NBP1-47609
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP2-47481
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-12897
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBL1-12154
Species: Hu
H00080333-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
H00003738-M01
Species: Hu
Applications: WB, ELISA
H00003753-M01
Species: Hu
Applications: WB, ELISA, RNAi
NBP1-42819
Species: Hu, Mu, Rt, Bv, Ca, Rb
Applications: WB, B/N, IP
NBP1-47649
Species: Mu, Rt
Applications: WB, IHC, IHC-P, IP

Publications for Kv4.2 Antibody (NBP1-47649)(3)

Reviews for Kv4.2 Antibody (NBP1-47649) (0)

There are no reviews for Kv4.2 Antibody (NBP1-47649). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Kv4.2 Antibody (NBP1-47649) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Kv4.2 Products

Bioinformatics Tool for Kv4.2 Antibody (NBP1-47649)

Discover related pathways, diseases and genes to Kv4.2 Antibody (NBP1-47649). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Kv4.2 Antibody (NBP1-47649)

Discover more about diseases related to Kv4.2 Antibody (NBP1-47649).
 

Pathways for Kv4.2 Antibody (NBP1-47649)

View related products by pathway.

PTMs for Kv4.2 Antibody (NBP1-47649)

Learn more about PTMs related to Kv4.2 Antibody (NBP1-47649).
 

Research Areas for Kv4.2 Antibody (NBP1-47649)

Find related products by research area.

Blogs on Kv4.2

There are no specific blogs for Kv4.2, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Kv4.2 Antibody (S57-1) and receive a gift card or discount.

Bioinformatics

Gene Symbol KCND2
Entrez
Uniprot