Kv1.4 Antibody (S13-31)

Images

 
Immunohistochemistry-Paraffin: Kv1.4 Antibody (S13-31) [NBP1-48304] - Tested on mouse brain. Weak positivity of some neurons with a bit of not specific background.

Product Details

Summary
Product Discontinued
View other related Kv1.4 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-48304
    • Availability
      Product Discontinued

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Kv1.4 Antibody (S13-31) Summary

Immunogen
Synthetic peptide 13-37 of rat Kv1.4
Epitope
NSHMPYGYAAQARARERERLAHSR
Specificity
The product is specific for ~98kDa. No cross-reactivity against Kv1.1, Kv1.2, Kv1.3, Kv1.5, and Kv1.6 expressed in transfected cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KCNA4
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-10 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 0.1-1.0 ug/ml
  • Immunoprecipitation 1:10-1:500
Publications
Read Publication using NBP1-48304.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 50% Glycerol
Preservative
0.09% Sodium Azide
Purity
Protein G purified

Alternate Names for Kv1.4 Antibody (S13-31)

  • cardiac potassium channel
  • fetal skeletal muscle potassium channel
  • HBK4
  • HK1
  • HPCN2HUKII
  • KCNA4L
  • KCNA8
  • KV1.4
  • PCN2
  • potassium channel 2
  • potassium voltage-gated channel subfamily A member 4
  • potassium voltage-gated channel, shaker-related subfamily, member 4
  • potassium voltage-gated channel, shaker-related subfamily, member 4-like
  • rapidly inactivating potassium channel
  • shaker-related potassium channel Kv1.4
  • type A potassium channel
  • Voltage-gated K(+) channel HuKII
  • Voltage-gated potassium channel HBK4
  • Voltage-gated potassium channel HK1
  • Voltage-gated potassium channel subunit Kv1.4

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influnce the duration of cardiac action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Kv1.4 Antibody (NBP1-48304)(1)

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Bioinformatics

Gene Symbol KCNA4
Entrez
Uniprot