Kremen-2 Overexpression Lysate (Denatured)

Images

 
KREMEN2 transfected lysate.
Lane 1: KREMEN2 transfected lysate (46.31 KDa) Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Kremen-2 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-KREMEN2 full-length
Gene
KREMEN2

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Kremen-2

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-KREMEN2 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Kremen-2 Overexpression Lysate (Denatured)

  • Dickkopf receptor 2
  • kremen protein 2
  • Kremen2
  • Kremen-2
  • kringle containing transmembrane protein 2
  • Kringle domain-containing transmembrane protein 2
  • KRM2Kringle-containing protein marking the eye and the nose
  • MGC10791
  • MGC16709

Background

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol KREMEN2
Entrez