In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
>90%, by SDS-PAGE
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 23.2 kDa (205aa) confirmed by MALDI-TOF. Immunoassay was reported in scientific literature. The His tag increases overall size to 205 residues.
23.2 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog
K-ras p21 protein
PR310 c-K-ras oncogene
transforming protein p21
v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.