KLHL12/C3IP1 Antibody (2G2)

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Western Blot: KLHL12/C3IP1 Antibody (2G2) [NBP2-22359] - using KLHL12 mouse mAb against Hela (1) cell lysate

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-22359
    • Availability
      Product Discontinued

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KLHL12/C3IP1 Antibody (2G2) Summary

Immunogen
Purified recombinant fragment of human KLHL12 expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KLHL12
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Protein G purified

Alternate Names for KLHL12/C3IP1 Antibody (2G2)

  • C3IP1kelch-like protein 12
  • CUL3-interacting protein 1
  • DKIR
  • FLJ27152
  • kelch-like 12 (Drosophila)
  • kelch-like protein C3IP1

Background

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Additional KLHL12/C3IP1 Products

Bioinformatics Tool for KLHL12/C3IP1 Antibody (NBP2-22359)

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Diseases for KLHL12/C3IP1 Antibody (NBP2-22359)

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Bioinformatics

Gene Symbol KLHL12