KIR2DL1/CD158a Antibody (HP-MA4) [PerCP/Cy5.5]

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Flow Cytometry: KIR2DL1/CD158a Antibody (HP-MA4) [PerCP/Cy5.5] [NBP1-42846] - Staining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) APC and Mouse IgG2b Isotype Control PerCP-Cy5.5 (left) or ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-42846
    • Availability
      Product Discontinued

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KIR2DL1/CD158a Antibody (HP-MA4) [PerCP/Cy5.5] Summary

Immunogen
The immunogen for this antibody was CD158a.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
This HP-MA4 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood. This can be used at 5 uL (0.25 ug) per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Reactivity Notes

This antibody is reactive to Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Purity
Protein A or G purified

Alternate Names for KIR2DL1/CD158a Antibody (HP-MA4) [PerCP/Cy5.5]

  • CD158 antigen-like family member A
  • CD158a antigen
  • CD158a
  • CD158Ankat1
  • cl-42
  • killer cell immunoglobulin-like receptor 2DL1
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  • killer Ig receptor
  • killer inhibitory receptor 2-2-1
  • KIR221
  • KIR2DL1
  • MHC class I NK cell receptor
  • Natural killer-associated transcript 1
  • NKAT
  • NKAT-1
  • NKAT1KIR-K64
  • p58 killer cell inhibitory receptor KIR-K64
  • p58 natural killer cell receptor clones CL-42/47.11
  • p58 NK cell inhibitory receptor NKR-K6,47.11
  • p58 NK receptor CL-42/47.11
  • p58.1 MHC class-I-specific NK receptor
  • p58.1

Background

The monoclonal antibody HP-MA4 recognizes the 58 kDa protein CD158a also known as KIR2DL2/S1. CD158a is a member of the family of killer cell immunoglobulin-like receptors (KIRs) comprising transmembrane glycoproteins expressed on NK cells and a subset of T cells. Many groups of KIRs exist including KIR2DL1-2, KIR3DS1, KIR2DL1-5, and KIR2DS1-5. The isoforms have either a short (S) or long (L) cytoplasmic domain which transduce either an activating or inhibitory signal, respectively. The ligand for CD158a is HLA-C. The HP-MA4 antibody has been shown to not cross react with other KIRs, despite the conservation of sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KIR2DL1
Entrez