KCNH1 Antibody [DyLight 650]

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Product Details

Summary
Product Discontinued
View other related KCNH1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-42816C
    • Availability
      Product Discontinued

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KCNH1 Antibody [DyLight 650] Summary

Immunogen
Synthetic peptide made to an internal portion of rat KCNH1 (within residues 400-450).[Swiss-Prot# Q63472]
Localization
Membrane; Multi-pass membrane protein.
Specificity
This antibody does not cross-react with Kv1.2.
Clonality
Polyclonal
Host
Rabbit
Gene
KCNH1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
Application Notes
This KCNH1 antibody is useful for Immunoprecipitation, Immunocytochemistry/Immunofluorescence and Western blot, where a band can be seen at ~110 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, mouse, rat, bovine and other vertebrates.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for KCNH1 Antibody [DyLight 650]

  • EAG channel 1
  • EAG1
  • EAGeag1
  • Ether-a-go-go potassium channel 1
  • ether-a-go-go, Drosophila, homolog of
  • hEAG1
  • h-eageag
  • Kv10.1
  • MGC142269
  • potassium channel, voltage-gated, subfamily H, member 1
  • potassium voltage-gated channel subfamily H member 1
  • potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Voltage-gated potassium channel subunit Kv10.1

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH1 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH1 is activated at the onset of myoblast differentiation. KCNH1 is highly expressed in brain and in myoblasts. Overexpression of KCNH1 may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of KCNH1 results in two transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol KCNH1