JNK3 Antibody

Images

 
Western Blot: JNK3 Antibody [NBP2-15001] - Sample (30 ug of whole cell lysate) A: IMR32 10% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: JNK3 Antibody [NBP2-15001] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-15001
    • Availability
      Product Discontinued

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JNK3 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human JNK3. The exact sequence is proprietary.
Predicted Species
Mouse (100%), Rat (100%), Bovine (100%), Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
MAPK10
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)

Reactivity Notes

Human. Predicted cross-reactivity based on sequence identity: Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for JNK3 Antibody

  • c-Jun N-terminal kinase 3
  • EC 2.7.11
  • EC 2.7.11.24
  • JNK3 alpha protein kinase
  • JNK3
  • JNK3A
  • JNK3FLJ12099
  • MAP kinase 10
  • MAP kinase p49 3F12
  • MAPK 10
  • MAPK10
  • MGC50974
  • mitogen-activated protein kinase 10
  • p493F12
  • p54bSAPK
  • PRKM10FLJ33785
  • SAPK1 beta
  • stress activated protein kinase beta
  • Stress-activated protein kinase JNK3

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MAPK10
Entrez
Uniprot