Novus Biologicals products are now on bio-techne.com

JAM-C Antibody (CRAM-18F26)

Images

 
There are currently no images for JAM-C Antibody (NBP3-11221).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ELISA, Flow, Func, IHC, IP
Clone
CRAM-18F26
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.1 mg/ml

Order Details

JAM-C Antibody (CRAM-18F26) Summary

Immunogen
The monoclonal antibody CRAM-18 F26 recognizes junctional adhesion molecule-C (JAM-C) also known as JAM-2, a 45 kD cell adhesion molecule (CAM).
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
JAM3
Purity
Protein G purified
Endotoxin Note
<24 EU/mg
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Functional
  • Immunoassay
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
Application Notes
For Immunohistochemistry and Flow Cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For inhibition of biological activity, dilutions have to be made according to the amounts of JAM-C to be inhibited.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
0.2 um filtered solution in PBS, 0.1% BSA
Preservative
No Preservative
Concentration
0.1 mg/ml
Purity
Protein G purified

Alternate Names for JAM-C Antibody (CRAM-18F26)

  • CD323
  • JAM-2
  • JAM3
  • JAMC
  • JAM-C
  • JAM-CFLJ14529
  • junctional adhesion molecule 3JAM-3
  • junctional adhesion molecule C

Background

The monoclonal antibody CRAM-18 F26 recognizes junctional adhesion molecule-C (JAM-C) also known as JAM-2, a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. Monoclonal antibody CRAM-18 F26 also reacts with human JAM-C. In humans, JAM-C expression is not restricted to endothelial cells, but is also expressed on human lymphocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

H00050848-M01
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, PLA, S-ELISA, WB
AF1074
Species: Hu, Mu
Applications: IHC, Neut, Simple Western, WB
AF1730
Species: Hu
Applications: AdBlk, CyTOF-ready, Flow, ICC
NB110-89474
Species: Bv, Ce, ChHa, Hu, Pm, Mu, Rt, RM
Applications: Dual ISH-IHC, Flow-CS, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, ISH, Simple Western, Single-Cell Western, WB
AF3449
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, WB
NBP1-85047
Species: Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-P, Simple Western, WB
H00050848-M01
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, PLA, S-ELISA, WB
AF629
Species: Hu
Applications: CyTOF-ready, Flow, InhibCellGro, WB
NBP2-02259
Species: Hu, Mu, Po, Rt
Applications: Flow-IC, Flow, ICC/IF
NBP1-87402
Species: Hu, Mu, Rt
Applications: ELISA, IHC, IHC-P, KD, WB
AF3628
Species: Hu, Mu, Rt
Applications: CyTOF-ready, Flow, ICC, IHC, WB
NBP1-88861
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, IP, Simple Western, WB
NB100-524
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
NBP2-79843
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
7268-CT
Species: Hu
Applications: BA
AF2654
Species: Mu
Applications: IHC, Simple Western, WB
137-PS
Species: Hu
Applications: BA
AF796
Species: Mu
Applications: AdBlk, IHC, WB

Publications for JAM-C Antibody (NBP3-11221) (0)

There are no publications for JAM-C Antibody (NBP3-11221).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for JAM-C Antibody (NBP3-11221) (0)

There are no reviews for JAM-C Antibody (NBP3-11221). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for JAM-C Antibody (NBP3-11221) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional JAM-C Products

Research Areas for JAM-C Antibody (NBP3-11221)

Find related products by research area.

Blogs on JAM-C

There are no specific blogs for JAM-C, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our JAM-C Antibody (CRAM-18F26) and receive a gift card or discount.

Bioinformatics

Gene Symbol JAM3