JAM-A Antibody (BV12)

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Product Details

Summary
Product Discontinued
View other related JAM-A Primary Antibodies

Order Details


    • Catalog Number
      NBP1-51784
    • Availability
      Product Discontinued

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JAM-A Antibody (BV12) Summary

Immunogen
The antibody reacts with Junctional Adhesion Molecule 1.
Isotype
IgG
Clonality
Monoclonal
Host
Rat
Gene
F11R
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
Application Notes
The antibody can be used for flow cytometry and immuno assays. The antibody is also useful for immunofluorescence on fixed cells.For flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.2 um purified material with PBS and 0.1% BSA
Preservative
0.02% Sodium Azide
Purity
Protein A or G purified

Alternate Names for JAM-A Antibody (BV12)

  • CD321 antigen
  • CD321
  • F11 receptor
  • F11R
  • JAM-1
  • JAM1CD321
  • JAMA
  • JAM-A
  • JCAMJAM
  • Junctional adhesion molecule 1Platelet F11 receptor
  • junctional adhesion molecule A
  • PAM-1
  • PAM-1KAT
  • Platelet adhesion molecule 1

Background

Junctional adhesion molecule-1 (JAM-1) also known as the mouse platelet F11-Receptor (F11R) is a cell adhesion molecule (CAM). JAM-1 is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-1 belongs together with JAM-2 and JAM-3 to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-1 plays a role in platelet aggregation, secretion, adhesion and spreading.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol F11R
Entrez