Jak3 Antibody


Western Blot: JAK3 Antibody [NBP1-61704] - Analysis of extracts from Jurkat cells, using JAK3 Antibody. The lane on the right is treated with the synthesized peptide.
Immunocytochemistry/ Immunofluorescence: JAK3 Antibody [NBP1-61704] - Analysis of A549 cells, using JAK3 Antibody. The picture on the right is treated with the synthesized peptide.
Immunohistochemistry-Paraffin: JAK3 Antibody [NBP1-61704] - Analysis of paraffin-embedded human brain tissue, using JAK3 Antibody. The picture on the right is treated with the synthesized peptide.

Product Details

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Jak3 Antibody Summary

The antiserum was produced against synthesized peptide derived from human JAK3. The immunogen region is: Internal.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • ELISA 1:1000
  • Immunocytochemistry/Immunofluorescence 1:100-1:500
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
Theoretical MW
125 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified

Alternate Names for Jak3 Antibody

  • EC 2.7.10
  • Jak3
  • JAK-3EC
  • JAKL
  • JAKLtyrosine-protein kinase JAK3
  • Janus kinase 3Leukocyte janus kinase
  • LJAK
  • L-JAKJanus kinase 3 (a protein tyrosine kinase, leukocyte)


Jak3 is a member of the Janus family tyrosine kinases (Jaks), whose function is to transduce extracellular signals from cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the signal transducers and activators of transcription (STATs). Activated STATs translocate to the nucleus to mediate gene transcription (1, 2). Jak3 is activated after binding to the gamma chain of Interleukin receptors, specifically IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. Jak3 has been implicated in mast cell-mediated immediate hypersensitivity reactions, autoimmune disorders, and acute lymphoblastic leukemia. Jak3 inhibitor has shown clinical potential as a new class of immunomodulatory agents with anti-leukemic and immunosuppressive properties (3).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


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Gene Symbol JAK3