Jak2 Antibody

Images

 
Western Blot: JAK2 Antibody [NBP2-17006] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 5% SDS PAGE gel, diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: Jak2 Antibody [NBP2-17006] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green- JAK2 protein stained by JAK2 antibody [N1], N-term diluted at 1:500. Blue: ...read more
Immunohistochemistry-Paraffin: Jak2 Antibody [NBP2-17006] - Paraffin-embedded human breast carcinoma JAK2 antibody [N1], N-term dilution: 1:500.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-17006
    • Availability
      Product Discontinued

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Jak2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human JAK2. The exact sequence is proprietary.
Localization
Endomembrane system; Peripheral membrane protein (By similarity)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
JAK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
131 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Mouse (86%), Porcine (88%), Rat (87%), Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1.24 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Jak2 Antibody

  • EC 2.7.10
  • EC 2.7.10.2
  • Jak2
  • JAK-2
  • Janus kinase 2Janus kinase 2 (a protein tyrosine kinase)
  • JTK10
  • tyrosine-protein kinase JAK2

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Jak2 Products

Bioinformatics Tool for Jak2 Antibody (NBP2-17006)

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Diseases for Jak2 Antibody (NBP2-17006)

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Blogs on Jak2.

Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...  Read full blog post.

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Bioinformatics

Gene Symbol JAK2
Entrez
Uniprot