Jagged 1 Antibody (HMJ1-29) [PE]

Images

 
Flow Cytometry: Jagged 1 Antibody (HMJ1-29) [PE] [NBP2-00234] - Staining of CD8+CD11c+ C57BL/6 splenocytes with 0.5 ug of Armenian Hamster IgG Isotype Control PE (blue histogram) or 0.5 ug of Anti-Mouse CD339 (Jagged 1) ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
HMJ1-29
Clonality
Monoclonal
Host
Armenian Hamster
Concentration
0.2 mg/ml

Order Details

Jagged 1 Antibody (HMJ1-29) [PE] Summary

Immunogen
The immunogen for this antibody is Jagged1.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
JAG1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Conjugate
PE
Format
PE (A=488, E=575)
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Publications
Read Publication using
NBP2-00234 in the following applications:

Reactivity Notes

Mouse

Alternate Names for Jagged 1 Antibody (HMJ1-29) [PE]

  • AGS
  • AHDMGC104644
  • Alagille syndrome
  • AWS
  • CD339 antigen
  • CD339
  • HJ1
  • JAG1
  • Jagged 1
  • Jagged1
  • JAGL1
  • protein jagged-1

Background

This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by ?-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Jagged 1 Antibody (NBP2-00234)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: FLOW.


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Secondary Antibodies

 

Isotype Controls

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol JAG1
Entrez
Uniprot

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