IRAK4 Antibody

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Immunohistochemistry-Paraffin: IRAK4 Antibody [NBP1-39956] - Staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-39956
    • Availability
      Product Discontinued

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IRAK4 Antibody Summary

Immunogen
A mixture of synthetic peptides containing amino acids 38-54 and 120-136 of mouse IRAK-4.
Specificity
A mixture of synthetic peptides containing amino acids 38-54 and 120-136 of mouse IRAK-4.
Clonality
Polyclonal
Host
Rabbit
Gene
IRAK4
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Mouse, Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 0.2% gelatin
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for IRAK4 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • interleukin-1 receptor-associated kinase 4
  • IPD1
  • IRAK4
  • IRAK-4
  • NY-REN-64
  • REN64
  • Renal carcinoma antigen NY-REN-64

Background

Interleukin-1 receptor (see IL1R; MIM 147810)-associated kinases (e.g., IRAK1; MIM 300283) are important mediators in the signal transduction of Toll-like receptor (TLR, e.g., TLR4; MIM 603030) and IL1R family members, collectively referred to as TIRs. IRAK4 functions in this signal transduction pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional IRAK4 Products

Bioinformatics Tool for IRAK4 Antibody (NBP1-39956)

Discover related pathways, diseases and genes to IRAK4 Antibody (NBP1-39956). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IRAK4 Antibody (NBP1-39956)

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Pathways for IRAK4 Antibody (NBP1-39956)

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PTMs for IRAK4 Antibody (NBP1-39956)

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Research Areas for IRAK4 Antibody (NBP1-39956)

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Blogs on IRAK4.

IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...  Read full blog post.

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Bioinformatics

Gene Symbol IRAK4
Entrez
Uniprot