IRAK4 Antibody (1D4)

Images

 
Western Blot: IRAK4 Antibody (1D4) [H00051135-M05] - Analysis of IRAK4 expression in K-562 (Cat # L009V1).
ELISA: IRAK4 Antibody (1D4) [H00051135-M05] - Detection limit for recombinant GST tagged IRAK4 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1D4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

IRAK4 Antibody (1D4) Summary

Immunogen
IRAK4 (AAH13316, 1 a.a. ~ 130 a.a) partial recombinant protein with GST tag.MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDK
Specificity
IRAK4
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IRAK4
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
Positive Control
K-562 Lysate (NB820-59464)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IRAK4 Antibody (1D4)

  • EC 2.7.11
  • EC 2.7.11.1
  • interleukin-1 receptor-associated kinase 4
  • IPD1
  • IRAK4
  • IRAK-4
  • NY-REN-64
  • REN64
  • Renal carcinoma antigen NY-REN-64

Background

Interleukin-1 receptor (see IL1R; MIM 147810)-associated kinases (e.g., IRAK1; MIM 300283) are important mediators in the signal transduction of Toll-like receptor (TLR, e.g., TLR4; MIM 603030) and IL1R family members, collectively referred to as TIRs. IRAK4 functions in this signal transduction pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for IRAK4 Antibody (H00051135-M05)

Discover related pathways, diseases and genes to IRAK4 Antibody (H00051135-M05). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on IRAK4.

IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...  Read full blog post.

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Bioinformatics

Gene Symbol IRAK4
Entrez
OMIM
Uniprot