IRAK2 Antibody


Western Blot: IRAK2 Antibody [NBP1-76934] - Analysis of IRAK2 in HeLa (H) and K562 (K) whole cell lysate with anti-IRAK2 (C2) using NBP1-76934 at 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: IRAK2 Antibody [NBP1-76934] - Immunofluorescence of IRAK-2 in Hela cells with IRAK-2 antibody at 10 ug/mL.
Immunocytochemistry/ Immunofluorescence: IRAK2 Antibody [NBP1-76934] - Immunocytochemical analysis IRAK2 in formalin-fixed HeLa cells using NBP1-76934 at 2 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
1 mg/ml

Order Details

IRAK2 Antibody Summary

Antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human IRAK2.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Application Notes
IRAK-2 antibody can be used for detection of IRAK2 by Western blot at 1-2 mg/ml. A 65 kDa band should be detected. This polyclonal antibody can also detect IRAK2 by immunohistochemistry at 2 mg/ml. Anti-IRAK2 has no cross response to IRAK.
Control Peptide
IRAK2 Peptide (NBP1-76934PEP)

Reactivity Notes


Alternate Names for IRAK2 Antibody

  • interleukin-1 receptor associated kinase-2
  • interleukin-1 receptor-associated kinase 2
  • interleukin-1 receptor-associated kinase-like 2
  • IRAK-2
  • MGC150550


The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappaB, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappaB activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-kappaB activation. Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory response. IRAK2 is expressed in a variety of human tissues.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol IRAK2

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