Integrin beta 5 Antibody - BSA Free

Immunohistochemistry-Paraffin: Integrin beta 5 Antibody [NBP1-88117] - Staining of human Endometrium shows moderate cytoplasmic positivity in cells in endometrial stroma.

Immunohistochemistry-Paraffin: Integrin beta 5 Antibody [NBP1-88117] - Staining of human Kidney shows moderate membranous and cytoplasmic positivity in cells in glomeruli.

Immunohistochemistry-Paraffin: Integrin beta 5 Antibody [NBP1-88117] - Staining of human Placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.

Staining of human Lymph node shows no positivity in non-germinal center cells as expected.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Integrin beta 5 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: KCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVL
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITGB5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Integrin beta 5 Protein (NBP1-88117PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Integrin beta 5 Antibody - BSA Free

• FLJ26658
• Integrin beta 5
• integrin beta-5
• integrin, beta 5
• ITGB5

Background

Integrins are heterodimers composed of noncovalently associated transmembrane

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin beta 5 Antibody (NBP1-88117)(2)

Publications using NBP1-88117

• Wen X, Chen S, Chen X et al. ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway Frontiers in oncology 2022-09-30 [PMID: 36249018] (IHC, WB, Human)
• Virga J, Szivos L et al. Extracellular matrix differences in glioblastoma patients with different prognoses. Oncol Lett 2019-01-01 [PMID: 30655832] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: ITGB5