Integrin beta 3/CD61 Antibody (Y2/51)

Images

 
Immunohistochemistry-Paraffin: Integrin beta 3/CD61 Antibody (Y2/51) [NBP1-22588] - Integrin beta 3 Antibody (Y2/51) [NBP1-22588] - IHC analysis of Integrin beta 3 in formalin fixed paraffin-embedded human bone marrow ...read more
Immunohistochemistry-Paraffin: Integrin beta 3/CD61 Antibody (Y2/51) [NBP1-22588] - Integrin beta 3 Antibody (Y2/51) [NBP1-22588] - IHC analysis of Integrin beta 3 in formalin fixed paraffin-embedded human bone marrow ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-22588
    • Availability
      Product Discontinued

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Integrin beta 3/CD61 Antibody (Y2/51) Summary

Immunogen
BALB/C mice were immunized with PHA-stimulated human mononuclear cells.
Localization
Cell membrane
Specificity
This antibody recognizes a glycoprotein of 110 kD molecular weight present on human platelets and also reacts with megakaryocytes and megakaryoblasts. The antigen is also present on endothelium and osteoclasts. The glycoprotein IIIa molecule produced by endothelium cells is identical in sequence to platelet glycoprotein IIIa.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ITGB3
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:25-1:50

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
No buffer
Preservative
Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for Integrin beta 3/CD61 Antibody (Y2/51)

  • CD61 antigen
  • CD61
  • GP3A
  • GP3Aplatelet glycoprotein IIIa
  • GPIIIA
  • GPIIIaintegrin beta-3
  • INGRB3
  • Integrin beta 3
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • ITG B3
  • ITGB3
  • Platelet membrane glycoprotein IIIa

Background

Human Integrin beta 3 (CD61) antigen is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex. The beta 3 integrin chain is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGB3
Entrez