Integrin beta 3/CD61 Antibody (HM beta 3.1)

Images

 
Flow Cytometry: Integrin beta 3/CD61 Antibody (HM beta 3.1) [NB100-65917] - Analysis of PE conjugate of NB100-65917. Staining of mouse peripheral blood platelets with HAMSTER ANTI MOUSE CD61:RPE
Flow Cytometry: Integrin beta 3/CD61 Antibody (HM beta 3.1) [NB100-65917] - Analysis using the FITC conjugate of NB100-65917. Staining of mouse peripheral blood platelets with HAMSTER ANTI MOUSE CD61:FITC.
Flow Cytometry: Integrin beta 3/CD61 Antibody (HM beta 3.1) [NB100-65917] - Analysis of Biotin conjugate of NB100-65917. Staining of mouse peripheral blood platelets with HAMSTER ANTI MOUSE CD61:BIOTIN

Product Details

Summary
Product Discontinued
View other related Integrin beta 3/CD61 Primary Antibodies

Order Details


    • Catalog Number
      NB100-65917
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Integrin beta 3/CD61 Antibody (HM beta 3.1) Summary

Immunogen
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
Specificity
NB100-65917 recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin (1).
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
ITGB3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:25
  • Immunoprecipitation 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Integrin beta 3/CD61 Antibody (HM beta 3.1)

  • CD61 antigen
  • CD61
  • GP3A
  • GP3Aplatelet glycoprotein IIIa
  • GPIIIA
  • GPIIIaintegrin beta-3
  • INGRB3
  • Integrin beta 3
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • ITG B3
  • ITGB3
  • Platelet membrane glycoprotein IIIa

Background

The CD61 protein product is the integrin beta chain beta 3. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrin alpha V/beta 3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase 2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha V/beta 3 recognizes the sequence R-G-D in a wide array of ligands. The alpha V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase 2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the sequence R-G-D in a wide array of ligands.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-37384
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P
NB110-68136
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready, Flow-IC
NBP1-81858
Species: Hu
Applications: WB, IHC, IHC-P
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NBP1-97507
Species: Hu, Mu, Rt, Bv, Ca
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP1-76544
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IHC-P
NBP1-88866
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NB300-500
Species: Hu, Mu, Rt, Po, Am, Bv, Ca, Dr
Applications: WB, IHC, IHC-Fr, IHC-P
NBP1-89296
Species: Hu
Applications: WB, IHC, IHC-P
NB600-1071
Species: Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NBP1-47602
Species: Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NB600-586
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB600-233
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP, PLA
NB100-65917
Species: Mu, Rt
Applications: Flow, IP

Publications for Integrin beta 3/CD61 Antibody (NB100-65917) (0)

There are no publications for Integrin beta 3/CD61 Antibody (NB100-65917).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Integrin beta 3/CD61 Antibody (NB100-65917) (0)

There are no reviews for Integrin beta 3/CD61 Antibody (NB100-65917). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Integrin beta 3/CD61 Antibody (NB100-65917) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Integrin beta 3/CD61 Products

Bioinformatics Tool for Integrin beta 3/CD61 Antibody (NB100-65917)

Discover related pathways, diseases and genes to Integrin beta 3/CD61 Antibody (NB100-65917). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Integrin beta 3/CD61 Antibody (NB100-65917)

Discover more about diseases related to Integrin beta 3/CD61 Antibody (NB100-65917).
 

Pathways for Integrin beta 3/CD61 Antibody (NB100-65917)

View related products by pathway.

PTMs for Integrin beta 3/CD61 Antibody (NB100-65917)

Learn more about PTMs related to Integrin beta 3/CD61 Antibody (NB100-65917).
 

Research Areas for Integrin beta 3/CD61 Antibody (NB100-65917)

Find related products by research area.

Blogs on Integrin beta 3/CD61

There are no specific blogs for Integrin beta 3/CD61, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Integrin beta 3/CD61 Antibody (HM beta 3.1) and receive a gift card or discount.

Bioinformatics

Gene Symbol ITGB3
Entrez