Integrin alpha V/CD51 Antibody (13C2) [FITC]

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Flow Cytometry: Integrin alpha V/CD51 Antibody (13C2) [FITC] [NBP1-28515] - Analysis of human HPV-16 transformed cell line HS-5.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-28515
    • Availability
      Product Discontinued

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Integrin alpha V/CD51 Antibody (13C2) [FITC] Summary

Immunogen
Cell suspension containing osteoclasts from osteoclastomas
Specificity
Human CD51
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGAV
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunocytochemistry

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Purity
Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for Integrin alpha V/CD51 Antibody (13C2) [FITC]

  • antigen identified by monoclonal L230
  • CD51 antigen
  • CD51
  • Integrin alpha V
  • integrin alpha-V
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • ITGAV
  • MSK8
  • Vitronectin Receptor alpha
  • Vitronectin receptor subunit alpha
  • VNRA
  • VNRADKFZp686A08142

Background

CD51 represents the 150 kDa integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit; it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (1-4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGAV
Entrez