Integrin alpha L/CD11a Antibody (MEM-25) [PE]


Flow Cytometry: Integrin alpha L/CD11a Antibody (MEM-25) [PE] [NB500-635] - Surface staining of human peripheral blood cells with anti-human CD11a (MEM-25) PE.

Product Details

Product Discontinued
View other related Integrin alpha L/CD11a Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Integrin alpha L/CD11a Antibody (MEM-25) [PE] Summary

Leucocytes from a patient suffering from a LGL-type leukemia (NM_001114380.1).
The antibody MEM-25 reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. HLDA IV; WS Code NL 209
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Flow Cytometry
Application Notes
Purity is > 95% (by SDS-PAGE). The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.
Positive Control
Integrin alpha L/CD11a Lysate (NBL1-12068)

Packaging, Storage & Formulations

Store at 4C in the dark.
PBS and 0.2% (w/v) high grade BSA (protease free)
15mM Sodium Azide
Protein A purified

Alternate Names for Integrin alpha L/CD11a Antibody (MEM-25) [PE]

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1


CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions. Blocking of LFA-1 function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases. For example, humanized anti-LFA-1 antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation; binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Mu
Species: Hu
Applications: WB, Flow, AdBlk, CyTOF-ready, ICC
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready
Species: Hu, Mu, Rt
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Single Cell Western
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
Species: Hu
Applications: WB, B/N, Flow, ICC/IF, IHC, IHC-Fr, IP
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, B/N, Flow, IHC, IHC-Fr
Species: Mu
Applications: Flow, IHC, IHC-P, IP, CyTOF-ready
Species: Hu, Mu
Applications: Flow, Func, In vitro, In vivo, CyTOF-ready, Flow-CS
Species: Hu, Mu, Rb(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, Flow-IC
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
Species: Hu, Ca, Mk
Applications: WB, IHC, IF
Species: Hu
Applications: Flow

Publications for Integrin alpha L/CD11a Antibody (NB500-635) (0)

There are no publications for Integrin alpha L/CD11a Antibody (NB500-635).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Integrin alpha L/CD11a Antibody (NB500-635) (0)

There are no reviews for Integrin alpha L/CD11a Antibody (NB500-635). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Integrin alpha L/CD11a Antibody (NB500-635) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional Integrin alpha L/CD11a Products

Bioinformatics Tool for Integrin alpha L/CD11a Antibody (NB500-635)

Discover related pathways, diseases and genes to Integrin alpha L/CD11a Antibody (NB500-635). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Integrin alpha L/CD11a Antibody (NB500-635)

Discover more about diseases related to Integrin alpha L/CD11a Antibody (NB500-635).

Pathways for Integrin alpha L/CD11a Antibody (NB500-635)

View related products by pathway.

PTMs for Integrin alpha L/CD11a Antibody (NB500-635)

Learn more about PTMs related to Integrin alpha L/CD11a Antibody (NB500-635).

Research Areas for Integrin alpha L/CD11a Antibody (NB500-635)

Find related products by research area.

Blogs on Integrin alpha L/CD11a

There are no specific blogs for Integrin alpha L/CD11a, but you can read our latest blog posts.

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our Integrin alpha L/CD11a Antibody (MEM-25) [PE] and receive a gift card or discount.


Gene Symbol ITGAL