Integrin alpha L/CD11a Antibody (HI111)

Images

 
Flow Cytometry: Integrin alpha L/CD11a Antibody (HI111) [NBP1-43440] - Analysis using the Biotin conjugate of NBP1-43440. Staining of Human peripheral blood lymphocytes with biotinylated HI111, followed by Sav-PE.
Flow Cytometry: Integrin alpha L/CD11a Antibody (HI111) [NBP1-43440] - Staining of normal human peripheral blood cells with Anti-Human CD11a FITC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (HI111) [NBP1-43440] - Analysis using the FITC conjugate of NBP1-43440. Staining of Human peripheral blood lymphocytes with HI111 FITC.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func, IHC, IHC-Fr
Clone
HI111
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Integrin alpha L/CD11a Antibody (HI111) Summary

Immunogen
The immunogen for this antibody was CD11a.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ITGAL
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Functional
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Application Notes
The HI111 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for Integrin alpha L/CD11a Antibody (HI111)

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

The HI111 monoclonal antibody reacts with human CD11a, the 180 kDa integrin alphaL, also known as the lymphocyte function associated antigen-1 (LFA-1) alpha chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin beta2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-43440AF405
Alexa Fluor 488 Labeled NBP1-43440AF488
Alexa Fluor 647 Labeled NBP1-43440AF647
Alexa Fluor 700 Labeled NBP1-43440AF700
Allophycocyanin Labeled NBP1-43440APC
DyLight 350 Labeled NBP1-43440UV
DyLight 405 Labeled NBP1-43440V
DyLight 488 Labeled NBP1-43440G
DyLight 680 Labeled NBP1-43440FR
DyLight 755 Labeled NBP1-43440IR
PE Labeled NBP1-43440PE
PerCP Labeled NBP1-43440PCP

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Bioinformatics

Gene Symbol ITGAL
Entrez