Integrin alpha 6/CD49f Antibody (CL6957)

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Analysis in human placenta and skeletal muscle tissues. Corresponding ITGA6 RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human uterine cervix shows weak to moderate basement membrane positivity in squamous epithelium.
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human placenta shows strong basement membrane positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human skeletal muscle shows no membranous positivity in striated muscle fibers as expected.
Immunohistochemistry-Paraffin: Integrin alpha 6/CD49f Antibody (CL6957) [NBP2-76523] - Staining of human prostate shows weak to moderate basement membrane positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
CL6957
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Integrin alpha 6/CD49f Antibody (CL6957) Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: APYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSS
Epitope
PSISIVGTLEAEKER
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGA6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88)% and Rat (86)%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, containing 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Integrin alpha 6/CD49f Antibody (CL6957)

  • CD49 antigen-like family member F
  • CD49f antigen
  • CD49f
  • DKFZp686J01244
  • FLJ18737
  • Integrin alpha 6
  • integrin alpha-6
  • integrin alpha6B
  • integrin, alpha 6
  • ITGA6
  • ITGA6B
  • Platelet gpl
  • VLA-6

Background

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ITGA6