Importin-8 Antibody

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Biological Strategies: Western Blot: Importin-8 Antibody [NB100-94994] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at for WB at 0.4 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
Validated by:
   

Biological Strategies

     

Order Details

Importin-8 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 987 and 1037 of human RAN binding protein 8 using the numbering given in entry NP_006381.2 (GeneID 10526).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IPO8
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Importin-8 Antibody

  • FLJ21954
  • FLJ26580
  • Imp8
  • importin 8
  • importin-8
  • RAN binding protein 8
  • Ran-binding protein 8
  • RanBP8
  • RANBP8imp8

Background

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IPO8
Entrez
Uniprot