IMP Dehydrogenase 2/IMPDH2 Antibody

Images

 
Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody [NBP1-32093] - Sample(30 ug of whole cell lysate)A:H12997. 5% SDS PAGE, antibody diluted at 1:500.
Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody [NBP1-32093] - (30 ug of whole cell lysate) A: H1299 B: Hep G2 7.5% SDS PAGE diluted at 1:500
Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody [NBP1-32093] - Sample (50 ug of whole cell lysate) A: Mouse brain 7. 5% SDS PAGE; antibody diluted at 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.17 mg/ml

Order Details

IMP Dehydrogenase 2/IMPDH2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human IMPDH2. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IMPDH2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000

Reactivity Notes

Expected cross reactivity based on sequence homology: Xenopus laevis (88%), Zebrafish (87%), Xenopus tropicalis (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.17 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IMP Dehydrogenase 2/IMPDH2 Antibody

  • EC 1.1.1.205
  • IMDH2
  • IMP (inosine 5'-monophosphate) dehydrogenase 2
  • IMP (inosine monophosphate) dehydrogenase 2
  • IMP Dehydrogenase 2
  • IMP Oxireductase 2
  • IMPD 2
  • IMPD2
  • IMPD2IMP oxireductase 2
  • IMPDH 2
  • IMPDH2
  • IMPDH-II
  • inosine 5' phosphate dehydrogenase 2
  • inosine monophosphate dehydrogenase type II
  • inosine-5'-monophosphate dehydrogenase 2

Background

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IMPDH2
Entrez