ILT5/CD85a/LILRB3 Antibody (4F9) [FITC]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-64064
    • Availability
      Product Discontinued

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ILT5/CD85a/LILRB3 Antibody (4F9) [FITC] Summary

Immunogen
Monocyte derived dendritic cells
Specificity
NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LILRB3
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10
Positive Control
ILT5/CD85a/LILRB3 Lysate (NBL1-12529)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein G purified

Alternate Names for ILT5/CD85a/LILRB3 Antibody (4F9) [FITC]

  • CD85 antigen-like family member A
  • CD85a antigen
  • CD85a
  • HL9Immunoglobulin-like transcript 5
  • ILT5
  • ILT-5
  • ILT5CD85a
  • Leukocyte immunoglobulin-like receptor 3
  • leukocyte immunoglobulin-like receptor subfamily B member 3
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
  • LILRB3
  • LIR3
  • LIR3CD85A
  • LIR-3MGC138403
  • member 3
  • Monocyte inhibitory receptor HL9
  • PIRB

Background

LILRB3 is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation. LILRB3 may act as receptor for class I MHC antigens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol LILRB3
Entrez