IL25 Antibody (1009420) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1009420
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

IL25 Antibody (1009420) [Alexa Fluor® 488] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human SF20
Met1-Leu173
Accession # Q969H8
Specificity
Detects human SF20 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL25 Antibody (1009420) [Alexa Fluor® 488]

  • C19orf10
  • chromosome 19 open reading frame 10
  • EUROIMAGE1875335
  • IL25
  • IL27
  • IL27w
  • interleukin 27 working designation
  • Interleukin-25
  • Ly6elg
  • MYDGF
  • myeloid-derived growth factor
  • R33729_1
  • SF20
  • Stromal cell-derived growth factor SF20
  • UPF0556 protein C19orf10

Background

Human SF20 (Stromal cell-derived growth factor SF20, C19orf10, MYDGF1, Myeloid-derived growth factor1 also formerly known as IL25) is a 15 kDa (predicted)  bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction. SF20 stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1 mediated signaling pathway. It is thought to inhibit cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway and is involved in endothelial cell proliferation and angiogenesis. Human SF20 shares 87% aa identity with mouse SF20.              

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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