IL18R1 Antibody (H44) [Biotin] Summary
Human NK cell line NK0 constitutively expressing IL-18 receptors
Protein A or G purified
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- Flow Cytometry 1:10-1:1000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:10-1:500
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume. Immunohistochemistry-frozen sections. It is recommended that the reagent be titrated for optimal performance for each application.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.2)
0.09% Sodium Azide
Protein A or G purified
Alternate Names for IL18R1 Antibody (H44) [Biotin]
- CD218 antigen-like family member A
- CD218a antigen
- cytokine receptor
- IL1RRPIL1 receptor-related protein
- interleukin 18 receptor 1
- interleukin-18 receptor 1
IL18R1 is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL18R1 alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL18R1 by flow cytometry and IHC.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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