Recombinant Human IL-9 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-43159
    • Availability
      Product Discontinued

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Recombinant Human IL-9 Protein Summary

Description
A partial protein corresponding to IL9.
Preparation
Method
E. coli.
Details of Functionality
This recombinant human IL-9 has been tested by bioassays using the cell line MO7e. The ED50 measured in the MO7e proliferation assay is typically less than 0.1 ng/ml, corresponding to a specific activity of greater than 10^7 Units/mg.
Protein/Peptide Type
Partial Recombinant Protein
Gene
IL9
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sterile liquid; 10 mM Phosphate, 150 mM NaCl with 1.0% BSA. 0.22 um filtered.
Preservative
0.09% Sodium Azide

Notes

Purity: Greater than 97%, as determined by SDS-PAGE

Alternate Names for Recombinant Human IL-9 Protein

  • Cytokine P40
  • HP40
  • IL9
  • IL-9
  • IL-9homolog of mouse T cell and mast cell growth factor 40
  • interleukin 9
  • interleukin-9
  • p40 cytokine
  • p40 T-cell and mast cell growth factor
  • P40
  • T-cell growth factor P40

Background

Interleukin-9 (IL-9) is a proinflammatory cytokine historically believed to be involved in type 2 immune responses. However, recent evidence suggests IL-9 may be secreted by a distinct T Helper lineage called Th9. These cells can either be derived from Th2 cells with TGF-beta or differentiated directly from nave CD4+ T cells with TGF-beta and IL-4. IL-9 is a member of the common cytokine receptor gamma chain-dependent family of cytokines which also includes IL-2, IL-4, IL-7, IL-15 and IL-21. Its pleiotropic effects on Th2 lymphocytes, B lymphocytes, mast cells, eosinophils and gut and airway epithelial cells have implicated IL-9 in asthma and other allergy-related disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol IL9
Entrez