IL-7R alpha/CD127 Antibody (73N4E10)

Western Blot: IL-7 R alpha/CD127 Antibody (73N4E10) [NBP2-25246] - Analysis an IL-17R recombinant protein fragment using IL7 Receptor alpha antibody at 2 ug/mL.

Product Discontinued

IL-7R alpha/CD127 Antibody (73N4E10) Summary

• Immunogen: Amino acids 145-235 of mouse IL-7R / CD127 were used as the immunogen for the antibody.
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: IL7R
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 2 - 5 ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for IL-7R alpha/CD127 Antibody (73N4E10)

• CD127 antigen
• CD127
• CD127ILRA
• CDW127
• IL-7 R alpha
• IL-7 receptor subunit alpha
• IL7R alpha
• IL-7R alpha
• IL-7R subunit alpha
• IL7R
• IL7RA
• IL-7Ra
• IL-7R-alpha
• interleukin 7 receptor alpha chain
• interleukin 7 receptor isoform H5-6
• interleukin 7 receptor
• interleukin-7 receptor subunit alpha

Background

IL-7R, or CD127, is often used to characterize regulatory T cells or Tregs. By phenotyping, IL-7R is inversely correlated with the high levels of the hallmark Treg transcription factor FoxP3. So lowered expression of IL-7R on the cell surface along with CD25 and CD4 in addition to FoxP3 internal expression is a major and routinely used technique for Treg cell studies. IL-7R residing on the surface enables enrichment and purification of Treg populations. Antibody to IL-7R is useful for phenotyping, identification, enumeration and purification of Tregs (1-3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL7R
• Uniprot:
  • NP_032398()