IL-7 R alpha/CD127 Antibody Summary
Synthetic peptides corresponding to IL7R (interleukin 7 receptor) The peptide sequence was selected from the middle region of IL7R.
Peptide sequence ESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCP.
This product is specific to Subunit or Isofrom: alpha.
Immunogen affinity purified
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- Western Blot 1:100-1:2000
This is a rabbit polyclonal antibody against IL7R and was validated on Western blot.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS and 2% Sucrose
0.09% Sodium Azide
Immunogen affinity purified
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Alternate Names for IL-7 R alpha/CD127 Antibody
- CD127 antigen
- IL-7 R alpha
- IL-7 receptor subunit alpha
- IL7R alpha
- IL-7R subunit alpha
- interleukin 7 receptor alpha chain
- interleukin 7 receptor isoform H5-6
- interleukin 7 receptor
- interleukin-7 receptor subunit alpha
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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