IL-7 R alpha/CD127 Antibody (73N4E10) - Azide Free Summary
Amino acids 145-235 of mouse IL-7R / CD127 were used as the immunogen for the antibody.
Protein G purified
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This product reacts with Mouse.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.5 mg/ml in sterile PBS
Protein G purified
Alternate Names for IL-7 R alpha/CD127 Antibody (73N4E10) - Azide Free
- CD127 antigen
- IL-7 R alpha
- IL-7 receptor subunit alpha
- IL7R alpha
- IL-7R subunit alpha
- interleukin 7 receptor alpha chain
- interleukin 7 receptor isoform H5-6
- interleukin 7 receptor
- interleukin-7 receptor subunit alpha
IL-7R, or CD127, is often used to characterize regulatory T cells or Tregs. By phenotyping, IL-7R is inversely correlated with the high levels of the hallmark Treg transcription factor FoxP3. So lowered expression of IL-7R on the cell surface along with CD25 and CD4 in addition to FoxP3 internal expression is a major and routinely used technique for Treg cell studies. IL-7R residing on the surface enables enrichment and purification of Treg populations. Antibody to IL-7R is useful for phenotyping, identification, enumeration and purification of Tregs (1-3).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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