Recombinant Human IL-7 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-43218
    • Availability
      Product Discontinued

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Recombinant Human IL-7 Protein Summary

Description
A partial protein corresponding to IL7.
Preparation
Method
E. coli expressed amino acids asp 26-his 177 of mature human IL-7 (accession # NM_000880).
Details of Functionality
This recombinant human IL-7 has been tested in bioassay of dose-dependent proliferation of PHA-activated human PBMCs, yielding an ED50 of approximately 2.0 ng/ml, corresponding to a specific activity of approximately 5x10^5Units/mg.
Protein/Peptide Type
Partial Recombinant Protein
Gene
IL7
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
20mM Tris, 50mM NaCl, pH 7.8 and 1.0% BSA as a carrier. 0.22 uM filtered.
Preservative
0.09% Sodium Azide

Notes

Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for Recombinant Human IL-7 Protein

  • IL7
  • IL-7
  • IL-7interleukin-7
  • interleukin 7
  • Lymphopoietin-1
  • PBGF

Background

Human IL-7, also called lymphopoietin 1 (LP-1), a pre-B cell growth factor, is a ~28 kDa factor produced by bone marrow and thymic stromal cell and spleen cells. IL-7 is a stromal cell-derived growth factor for progenitor B cells and T cells. The main population in the thymus responsive to IL-7 is CD4-CD8-. It also stimulates proliferation and differentiation of mature T cells and NK cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol IL7
Entrez