Recombinant Mouse IL-4 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99808
    • Availability
      Product Discontinued

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Recombinant Mouse IL-4 Protein Summary

Description
A recombinant protein corresponding to 120 amino acids of Mouse IL-4

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
Preparation
Method
E. coli
Details of Functionality
The EDSO determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is <.2.0 ng/ml, corresponding to a specific activity of >5 x 105 units/mg.
Protein/Peptide Type
Recombinant Protein
Gene
IL4
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
No additives.
Concentration
Lyoph
Reconstitution Instructions
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.

Notes

After reconstituted, dilute further with other aqueous solutions.

Alternate Names for Recombinant Mouse IL-4 Protein

  • B cell growth factor 1
  • BCDF
  • B-cell stimulatory factor 1
  • BCGF1
  • BCGF-1
  • binetrakin
  • BSF1
  • BSF-1
  • IL4
  • IL-4
  • IL-4B_cell stimulatory factor 1
  • interleukin 4
  • interleukin-4
  • Lymphocyte stimulatory factor 1
  • MGC79402
  • pitrakinra

Background

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol IL4
Entrez
Uniprot