IL-4 Partial Recombinant Protein Summary
A partial protein corresponding to IL4.
E. coli expressed amino acids his 21-ser140 of mature mouse IL-4 (accession # NM_021283).
|Details of Functionality
The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 1250 pg/mL. This corresponds to a specific activity of greater than or equal to 8 x 10^5 Units/mg.
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
20mM Phosphate, 0.38M NaCl, pH 6.5, with no carriers or perservatives. 0.22 um filtered.
Please see the vial label for concentration. If unlisted please contact technical services.
The recombinant mouse IL-4 has been tested by sandwich ELISA using the anti-mouse IL-4 antibody pair (11B11/BVD6-24G2).
Recombinant mouse IL-4 is biologically active and can promote proliferation of mouse T lymphocytes in culture.
This protein was made to the mouse sequence.
Purity: Greater than 98%, as determined by SDS-PAGE
Alternate Names for IL-4 Partial Recombinant Protein
- B cell growth factor 1
- B-cell stimulatory factor 1
- IL-4B_cell stimulatory factor 1
- interleukin 4
- Lymphocyte stimulatory factor 1
Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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