IL-32 Antibody Summary
Synthetic peptide, corresponding to amino acids 200-2450 of Human IL-32.
IL-32 (K226) pAb detects endogenous levels of IL-32 protein.
Immunogen affinity purified
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- Western Blot 1:500-1:1000
- Immunohistochemistry 1:50-1:200
- Immunohistochemistry-Paraffin 1:50-1:200
Western blot (WB) analyzes of IL-32 (K226) pAb in extracts from HepG2 cells.
Immunohistochemistry (IHC) analyzes of IL-32 (K226) pAb in paraffin-embedded human lung carcinoma tissue.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
Immunogen affinity purified
Alternate Names for IL-32 Antibody
- interleukin 32
- interleukin-32 theta
- natural killer cell transcript 4
- Natural killer cells protein 4
- Tumor necrosis factor alpha-inducing factor
The interleukins make up a large family of well characterized cytokines, primarily of hematopoietic cell origin. The interleukins are secreted by immune cells (mainly macrophages, B cells and T cells) that regulate a wide range of immune system functions. Interleukin-32 (IL-32), also designated Natural Killer (NK) cell transcript 4 (nk4), may play a role in inflammatory responses such as lymphocyte activation. IL-32 is secreted following stimulation with inflammatory cytokines such as IL-1beta and IFN-gamma, and by NK cells after exposure to IL-12 and IL-18. It also induces production of IL-1beta, TNFalpha, MIP-2 and IL-6. Expression of IL-32 increases after activation of T cells by mitogens or activation of NK cells by IL-2. The IL-32 protein contains three potential N-myristoylation sites, a tyrosine sulfation site, an RGD cellattachment sequence and multiple putative phosphorylation sites. Human IL-32 exists as four isoforms.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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