IL-31 Partial Recombinant Protein


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Product Details

Applications IA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

IL-31 Partial Recombinant Protein Summary

A partial protein corresponding to IL31.
E. coli-expressed protein consisting of amino acids Thr24-Cys163 of mature mouse IL-31 (accession # XM_132344).
Details of Functionality
Testing in progress.
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; 40% Acetonitrile, 0.1% TFA, 0.22 um filtered.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.


Application Notes
Currently there is no reliable bioassay available for the recombinant mouse IL-31.

Reactivity Notes

This protein was made to the human sequence.


Purity: Greater than 98% as determined by SDS-PAGE

Alternate Names for IL-31 Partial Recombinant Protein

  • IL31
  • IL-31interleukin-31
  • interleukin 31


Interleukin-31 (IL-31) is a member of the gp130/IL-6 family of cytokines that is produced predominantly, but not exclusively, by activated Th2 cells. It binds to a heterodimeric receptor complex consisting of IL-31RA (GPL, GLM-R), a gp130-like molecule, and oncostatin M receptor (OSMR). This receptor complex is expressed constitutively on keratinocytes and epithelial cells and can be upregulated on monocytes by IFN-gamma or LPS. IL-31 signaling activates the Jak/STAT signaling pathway, including STAT1, STAT3, and STAT5, as well as the PI3 kinase/AKT and MAP kinase pathways. Mouse IL-31 shares 31% amino acid identity with human IL-31 but it does not bind to the human IL-31 receptor.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol IL31

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