IL-3 R alpha/CD123 Antibody (5B11) [PerCP]

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Product Details

Summary
Product Discontinued
View other related IL-3 R alpha/CD123 Primary Antibodies

Order Details


    • Catalog Number
      NB100-63384PCP
    • Availability
      Product Discontinued

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IL-3 R alpha/CD123 Antibody (5B11) [PerCP] Summary

Immunogen
CTLL cells transfected with mouse CD123.
Localization
Type I membrane protein
Specificity
NB100-63384 recognizes murine CD123, which is the 70kD alpha chain of the interleukin-3 receptor (IL-3R). CD123 is expressed on haematopoietic progenitors and most myeloid cells including basophils and mast cells. Certain mouse strains including A/J, AKR/J and NZB/B1NJ are reported to have low levels of CD123 expression due to aberrant splicing of the IL-3R alpha subunit gene. In mouse, CD123 can associate with either the common beta subunit CDw131 or with the murine IL-3 beta subunit to form a high affinity receptor for IL-3. IL-3 can bind to CD123 itself but with low affinity. Binding of IL-3 to the IL-3 receptor complex induces the proliferation and differentiation of haematopoietic cells. Clone 5B11 does not block the binding of IL-3 to the high affinity IL-3 receptor.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
IL3RA
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IL-3 R alpha/CD123 Antibody (5B11) [PerCP]

  • CD123 antigen
  • CD123
  • hIL3Ra
  • hIL-3Ra
  • IL-3 R alpha
  • IL-3 receptor subunit alpha
  • IL3R alpha
  • IL-3R subunit alpha
  • IL3R
  • IL3RA
  • IL-3Ra
  • IL-3R-alpha
  • IL3RAY
  • IL3RX
  • IL3RY
  • interleukin 3 receptor, alpha (low affinity)
  • interleukin-3 receptor subunit alpha
  • MGC34174

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol IL3RA
Entrez