IL-27 Antibody

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Product Details

Summary
Product Discontinued
View other related IL-27 Primary Antibodies

Order Details


    • Catalog Number
      NBP2-03945
    • Availability
      Product Discontinued

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IL-27 Antibody Summary

Immunogen
Amino acids 141-175 of human IL-27 protein was used as the immunogen.
Epitope
RLDLRDLQRHLRFQV
Clonality
Polyclonal
Host
Rabbit
Gene
IL27
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:1000

Reactivity Notes

Cow, Mouse, Rat
The amino acid sequence used as immunogen is 100% identical in human, dog and chimpanzee, 93% identical in mouse, rat and cow.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.1 ml crude whole Rabbit sera with 50% Glycerol
Preservative
0.025% Sodium Azide
Purity
Unpurified

Alternate Names for IL-27 Antibody

  • IL-27 p28 subunit
  • IL-27 subunit alpha
  • IL27
  • IL-27
  • IL27A
  • IL-27-A
  • IL27-A
  • IL27p28
  • IL30
  • interleukin 27
  • interleukin 30
  • interleukin-27 subunit alpha
  • MGC71873
  • p28IL-27A

Background

IL-27 is a 243 aa, novel heterodimeric cytokine belonging to the IL-6/IL-12 family and produced by activated antigen-presenting cells. It is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) and p28. Recent reports suggest that IL-27 is a potent inhibitor of HIV-1 replication in PBMCs, CD4 (+) T cells and macrophages. It has antiangiogenic activity, which plays an important role in its antitumor and antimetastatic activities. It is also responsible for early regulation of Th1 adaptive immune response. It strongly synergizes with IL-12 to trigger IFN-gamma production of naive CD4 (+) T cells and drives rapid clonal expansion of naive but not memory CD4 (+) T cells through the cytokine receptor WSX-1/TCCR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Additional IL-27 Products

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Blogs on IL-27.

Ly6G - a marker for monocytes, granulocytes and neutrophils
Ly6G (Lymphocyte antigen 6 complex locus G6D) is a 21-25kD glycosylphosphatidylinositol (GPI)-linked differentiation antigen that is expressed by myeloid-derived cells in a tightly developmentally-regulated manner in the bone marrow. Monocytes express...  Read full blog post.

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Bioinformatics

Gene Symbol IL27
Entrez