IL-22 R alpha 1 Antibody

Images

 
Western Blot: IL-22 R alpha 1 Antibody [NBP1-76724] - Analysis of IL-22 receptor expression in human HepG2 cell lysate with IL-22 receptor antibody at (A) 0.5 and (B) 1 ug /ml.
Immunocytochemistry/ Immunofluorescence: IL-22 R alpha 1 Antibody [NBP1-76724] - Rat kidney tissue with IL-22R antibody at 20 ug/ml.
Immunohistochemistry: IL-22 R alpha 1 Antibody [NBP1-76724] - Staining of rat kidney tissue with antibody at 5 ug/mL.
Western Blot: IL-22 R alpha 1 Antibody [NBP1-76724] - Human HepG2 cell lysate with IL-22RA1 antibody at 1 ug /ml.
Immunocytochemistry/ Immunofluorescence: IL-22 R alpha 1 Antibody [NBP1-76724] - Immunofluorescence of IL-22 receptor in HepG2 cells with IL-22 receptor antibody at 10 ug/mL.
Immunocytochemistry/ Immunofluorescence: IL-22 R alpha 1 Antibody [NBP1-76724] - Immunofluorescence:HepG2 cells with IL-22RA1 receptor antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

IL-22 R alpha 1 Antibody Summary

Immunogen
Antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor. The immunogen is located within the first 50 amino acids of IL-22 Receptor.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IL22RA1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunohistochemistry 5 ug/mL
  • Immunohistochemistry-Paraffin 5 ug/mL
Application Notes
IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 0.5 to 1 mg/ml. An approximately 62 kDa band can be detected.
Theoretical MW
64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
IL-22 R alpha 1 Peptide (NBP1-76724PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IL-22 R alpha 1 Antibody

  • CRF2-9
  • CRF2-9interleukin 22 receptor
  • Cytokine receptor class-II member 9
  • Cytokine receptor family 2 member 9
  • IL-22 R alpha 1
  • IL-22 receptor subunit alpha-1
  • IL22R alpha 1
  • IL22R
  • IL22R1
  • IL22RA1
  • IL-22Ra1
  • IL-22R-alpha-1
  • IL-TIF-R1
  • interleukin 22 receptor, alpha 1
  • interleukin-22 receptor subunit alpha-1
  • zcytoR11

Background

A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL22RA1
Entrez
Uniprot