IL-21 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

IL-21 Antibody Summary

Immunogen
Amino acids 33-111 of IL21.
Localization
Secreted
Specificity
IL21
Clonality
Polyclonal
Host
Chicken
Gene
IL21
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:200
  • ELISA 0.1 ug/ml
Application Notes
ELISA and Western Blot Predicted molecular weight 19 kDa. Recommended starting dilution for Western blot analysis is 1:500, for tissue or cell staining 1:200.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IL-21 Antibody

  • IL21
  • IL-21
  • IL-21Za11interleukin-21
  • interleukin 21
  • interleukin-21 isoform

Background

A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. IL21 has been found to be a powerful growth factor for naive B cells. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional IL-21 Products

Bioinformatics Tool for IL-21 Antibody (NB300-362)

Discover related pathways, diseases and genes to IL-21 Antibody (NB300-362). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IL-21 Antibody (NB300-362)

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Pathways for IL-21 Antibody (NB300-362)

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PTMs for IL-21 Antibody (NB300-362)

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Research Areas for IL-21 Antibody (NB300-362)

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Blogs on IL-21.

Perforin Antibodies Reveal Links to Apoptosis and Immune Response
Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel...  Read full blog post.

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Bioinformatics

Gene Symbol IL21
Entrez