IL-20 Antibody

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Western Blot: IL-20 Antibody [NBP1-19744] - Extracts from A549 cells.

Product Details

Summary
Product Discontinued
View other related IL-20 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19744
    • Availability
      Product Discontinued

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IL-20 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 30-78 of Human IL-20.
Clonality
Polyclonal
Host
Rabbit
Gene
IL20
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (approx. pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IL-20 Antibody

  • Cytokine Zcyto10
  • IL10D
  • IL20
  • IL-20
  • IL-20ZCYTO10four alpha helix cytokine
  • interleukin 20
  • interleukin-20
  • MGC96907

Background

The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-lamda. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ralpha and IL-20Rbeta. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ralpha and IL-20Rbeta all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional IL-20 Products

Bioinformatics Tool for IL-20 Antibody (NBP1-19744)

Discover related pathways, diseases and genes to IL-20 Antibody (NBP1-19744). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IL-20 Antibody (NBP1-19744)

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Calculators

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Bioinformatics

Gene Symbol IL20
Entrez
Uniprot