Recombinant Mouse IL-2 Protein Summary
A partial protein corresponding to IL2.
E. coli expressed amino acids Ala 21-Gln 169 of mouse IL-2 (accession # MMIL04).
|Details of Functionality
ED50 measured in a CTLL-2 proliferation assay is typically 100 pg/ml, corresponding to a specific activity of (1 x 10^7U/mg).
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
This reagent has been tested by sandwich ELISA using anti-mouse IL-2 antibody pair (JES6-1A12/JES6-5H4).
This protein was made to the mouse sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid; 5 mM citric acid, 5 mM NaHPO4, 0.4 M NaCl, pH 4.0, 1 mM DTT, with no carriers. 0.22 uM filtered.
Purity: Greater than 98%, as determined by SDS-PAGE
Alternate Names for Recombinant Mouse IL-2 Protein
- interleukin 2
- involved in regulation of T-cell clonal expansion
- T cell growth factor
- T-cell growth factor
Mouse IL-2 (also known as TCGF) is an ~17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: Flow, Func, In vitro, In vivo, CyTOF-ready, Flow-CS
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
Applications: WB, Flow, CyTOF-ready, ICC
Applications: WB, IHC, IHC-P
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
Species: Hu, Mu
Applications: WB, ICC/IF, IHC-P
Applications: WB, AgAct
Applications: WB, ELISA, ICC/IF
Applications: WB, ICC/IF, IHC, IHC-P
Publications for IL-2 Protein (NBP1-42928) (0)
There are no publications for IL-2 Protein (NBP1-42928).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for IL-2 Protein (NBP1-42928) (0)
There are no reviews for IL-2 Protein (NBP1-42928).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for IL-2 Protein (NBP1-42928) (0)
Additional IL-2 Products
Bioinformatics Tool for IL-2 Protein (NBP1-42928)
Discover related pathways, diseases and genes to IL-2 Protein (NBP1-42928). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on IL-2.
The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins. The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein... Read full blog post.
iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti... Read full blog post.