Recombinant IL-17C Protein

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Product Details

Summary
Product Discontinued
View other related IL-17C Peptides and Proteins

Order Details


    • Catalog Number
      NBP1-43210
    • Availability
      Product Discontinued

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Recombinant IL-17C Protein Summary

Description
A partial protein corresponding to IL17C.
Preparation
Method
Insect cell expressed His tag + H15-Q194 of mature mouse IL-17C (accession #NP_665833).
Details of Functionality
Testing in progress.
Protein/Peptide Type
Partial Recombinant Protein
Gene
IL17C
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Applications/Dilutions

Application Notes
Currently there is no reliable bioassay available for the recombinant mouse IL-17C.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
20 mM Phosphate, 0.2 M NaCl, pH 6.0, with 1.0% BSA.
Preservative
0.09% Sodium Azide

Notes

Purity: Greater than 97% as determined by SDS-PAGE

Alternate Names for Recombinant IL-17C Protein

  • CX2
  • Cytokine CX2
  • IL17C
  • IL-17C
  • IL-17CMGC126884
  • interleukin 17C
  • interleukin-17C
  • MGC138401

Background

IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1beta from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Mouse IL-17C cDNA encodes a 194 amino acid protein with a putative 14 amino acid signal peptide. The recombinant mouse IL-17C is a disulfide-linked homodimer composed of a 20.2 kDa monomeric subunit.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol IL17C
Entrez