Recombinant IL-17C Protein Summary
A partial protein corresponding to IL17C.
Insect cell expressed AQPAVHHHHHHSAGIEGR+His19-Val197 of mature human IL-17C (accession #NM_013278).
|Details of Functionality
Testing in progress.
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Purity is greater than 98% as determined by SDS-PAGE. Endotoxin level is less than 0.01 ng/ug cytokine as determined by the LAL assay.
This protein was made to the human sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
20 mM Phosphate, 0.2 M NaCl, pH 6.0, with 1.0% BSA.
0.09% Sodium Azide
Purity: Greater than 98% as determined by SDS-PAGE
Alternate Names for Recombinant IL-17C Protein
- Cytokine CX2
- interleukin 17C
IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1beta from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Human IL-17C cDNA encodes a 197 amino acid protein with a putative 18 amino acid signal peptide. The recombinant human IL-17C is a disulfide-linked homodimer composed of a 19.8 kDa monomeric subunit.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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