Recombinant Human IL-17C Protein Summary
A partial protein corresponding to IL17C.
Insect cell expressed AQPAVHHHHHHSAGIEGR+His19-Val197 of mature human IL-17C (accession #NM_013278).
|Details of Functionality
Testing in progress.
| Protein/Peptide Type
Partial Recombinant Protein
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Currently there is no reliable bioassay available for the recombinant human IL-17C. Purity is > 98% as determined by SDS-PAGE.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This protein was made to the human sequence.
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
20 mM Phosphate, 0.2 M NaCl, pH 6.0, 0.22 um filtered.
0.09% Sodium Azide
Purity: Greater than 98% as determined by SDS-PAGE
Alternate Names for Recombinant Human IL-17C Protein
- Cytokine CX2
- interleukin 17C
IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1beta from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Human IL-17C cDNA encodes a 197 amino acid protein with a putative 18 amino acid signal peptide. The recombinant human IL-17C is a disulfide-linked homodimer composed of a 19.8 kDa monomeric subunit.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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