IL-15 Overexpression Lysate (Denatured) Summary
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
In 50mM Tris-HCl, 2%SDS, 10% glycerol, 2% 2-mercaptoethanol, pH 6.8.
This antibody is useful for Western Blot
Lysate Details for IL-15
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for IL-15 Overexpression Lysate (Denatured)
- interleukin 15
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed
for 6 months from date of receipt.
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