Western blot shows lysates of human placenta tissue and human testis tissue. PVDF membrane was probed with 5 µg/mL of Mouse Anti-Human IL‑13 R alpha 2 Monoclonal Antibody (Catalog # MAB614) followed by HRP-conjugated ...read more
IL-13 R alpha 2 Antibody (83834) [Unconjugated] Summary
Mouse myeloma cell line NS0-derived recombinant human IL‑13 R alpha 2 Cys22-Leu342 Accession # Q14627
Detects human IL-13 R alpha 2 in direct ELISAs and Western blots. In Western blots, this antibody shows approximately 5% cross‑reactivity with recombinant human (rh) IL‑4 R and rhIL‑9 R and no cross-reactivity with rhIL‑5 R alpha, rhIL‑5 R beta, rhIL‑13 R alpha 1, or recombinant mouse IL‑13 R alpha 2.
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Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for IL-13 R alpha 2 Antibody (83834) [Unconjugated]
cancer/testis antigen 19
IL-13 R alpha 2
IL-13 receptor subunit alpha-2
IL13R alpha 2
IL-13R subunit alpha-2
interleukin 13 binding protein
interleukin 13 receptor alpha 2 chain
interleukin 13 receptor, alpha 2
interleukin-13 receptor subunit alpha-2
Two type I membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with high affinity. The lower affinity IL-13 binding protein is now referred to as IL-13 R alpha 1 and is also known as CD213a. IL-13 R alpha 1 combines with IL-4 R alpha to form a high affinity receptor complex capable of transducing an IL-13-dependent proliferative signal. The higher affinity IL-13 binding protein, now referred to as IL-13 R alpha 2, does not induce a signal and acts as a decoy receptor.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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