Recombinant Human IL-13 Protein (NBP1-42914)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-42914
    • Availability
      Product Discontinued

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Recombinant Human IL-13 Protein Summary

Description
A partial protein corresponding to IL13.
Preparation
Method
E. coli expressed amino acids Gly 21-Leu 132 of mature human IL-13 (accession #NM_002188).
Details of Functionality
The ED50 as determined by the dose-dependent proliferation of TF-1 cells is typically 1.0-5.0 ng/ml, corresponding to a specific activity of 0.2-1.0 x 10^6 Units/mg.
Protein/Peptide Type
Partial Recombinant Protein
Gene
IL13
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Applications/Dilutions

Application Notes
This recombinant human IL-13 has been tested by a sandwich ELISA using the anti-human IL-13 ELISA antibody pair (PVM13-1 / polyclonal anti-human IL-13), and in bioassays using the IL-13 responsive cell line TF-1.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sterile liquid; 10 mM sodium phosphate, pH 7.2, 150 mM NaCl, with no carriers. Sterile filtered.
Preservative
No Preservative

Notes

Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for Recombinant Human IL-13 Protein

  • ALRHMGC116789
  • BHR1interleukin-13
  • IL13
  • IL-13
  • IL-13MGC116788
  • interleukin 13
  • MGC116786
  • NC30
  • P600

Background

Human interleukin-13 (IL-13), also known as NC30, is a 12.5 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression and suppression of inflammatory cytokine expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Product General Protocols

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Blogs on IL-13.

FLICE, FLICE, baby
Cell death via apoptosis is a fundamental cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. All caspases exist in a precursor form compose...  Read full blog post.

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Bioinformatics

Gene Symbol IL13
Entrez